Combination has superior activity attributed to Sulbactum, that potentiates the bactericidal activity of Cefoperazone'
This combination shows a marked degree of synergy against organism that are resistance to cefoperazone alone, including actinobacter & enterobacter species
Shows least resistance & highest percentage sensitivity against 277 strains
Cefoperazone-sulbactam shows high success rate 91.9% as compared to ceftazidime- amikacin - metronidazole (81.8%)against E.coli & klebsiella species in intra-abdominal infection