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Liposomal Amphotericin B injection 50mg

Price 500 INR/ Bottle

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MOQ : 50-100 Bottles

Liposomal Amphotericin B injection 50mg Specification

Life Span
24 months from date of manufacture

Indication
Invasive fungal infections (aspergillosis, candidiasis, cryptococcosis), visceral leishmaniasis

Pacakaging (Quantity Per Box)
One vial per box

Packaging Type
Glass vial with sterile stopper and flip-off seal

Brand Name
Varies by manufacturer

Salt Composition
Liposomal Amphotericin B

Dosage Form
Injection

Origin of Medicine
India

Drug Type
General Medicines

Ingredients
Liposomal Amphotericin B 50mg, Excipients Q.S.

Physical Form
Lyophilized Powder for Injection

Function
Antifungal and antileishmanial

Recommended For
Systemic fungal infections, treatment of leishmaniasis

Dosage
As directed by physician; typically 3-5 mg/kg daily

Dosage Guidelines
Reconstitute before administration and infuse slowly as per protocol

Suitable For
Adults and pediatric patients

Quantity
10000 Boxes

Storage Instructions
Store below 25C, protect from light

Reconstitution Instructions
Add 12 mL sterile water for injection to yield 4 mg/mL concentration

Special Precautions
Use with caution in patients with renal impairment or electrolyte imbalance

Side Effects
May cause nephrotoxicity, infusion-related reactions, electrolyte disturbances

Contraindications
Known hypersensitivity to amphotericin B or any component

Color of Lyophilized Cake
White to off-white

Marketed By
As per distributor

Vial Content
Lyophilized powder, requires reconstitution with sterile water for injection

Route of Administration
Intravenous infusion only

Infusion Time
Infuse over 2 hours minimum

Liposomal Amphotericin B injection 50mg Trade Information

Minimum Order Quantity
50-100 Bottles

Payment Terms
Cash in Advance (CID)

Supply Ability
10000 Bottles Per Day

Delivery Time
2 Days

Packaging Details
1 vial

Main Domestic Market
All India

Certifications
gmp

About Liposomal Amphotericin B injection 50mg

Amphotericin B liposomal injection is used to treat fungal infections such as cryptococcal meningitis (a fungal infection of the lining of the spinal cord and brain) and visceral leishmaniasis (a parasitic disease that usually affects spleen, liver, and bone marrow) in certain people

Precise Reconstitution and Administration

This product is strictly for intravenous infusion. Prior to use, reconstitute the lyophilized powder by adding 12 mL of sterile water for injection, yielding a concentration of 4 mg/mL. The resultant solution should be infused slowly over a minimum of 2 hours. This process ensures effective and safe delivery of the medication to target invasive fungal and parasitic infections.

Therapeutic Applications and Advantages

Liposomal Amphotericin B is recognized for its broad-spectrum action against severe fungal infections and leishmaniasis. The liposomal formulation notably reduces nephrotoxicity compared to conventional amphotericin B, allowing for higher doses and improved tolerability. The product is suitable for both adult and pediatric patients, making it a versatile therapeutic option.

FAQ's of Liposomal Amphotericin B injection 50mg:

Q: How is Liposomal Amphotericin B injection 50mg prepared for administration?

A: To prepare Liposomal Amphotericin B for intravenous infusion, add 12 mL of sterile water for injection to the lyophilized powder, giving a 4 mg/mL solution. After reconstitution, the medication is infused over at least 2 hours.

Q: What medical conditions are treated with this injection?

A: This medication is recommended for treating invasive fungal infections such as aspergillosis, candidiasis, cryptococcosis, and for visceral leishmaniasis, under the guidance of a qualified physician.

Q: When should Liposomal Amphotericin B not be used?

A: It should not be administered to patients with known hypersensitivity to amphotericin B or any of its components.

Q: Where should this product be stored to maintain efficacy?

A: The vials should be stored below 25C and protected from light to ensure potency until the expiry date, which is 24 months from the date of manufacture.

Q: What are the main side effects associated with this medication?

A: While this formulation is less nephrotoxic, potential side effects include nephrotoxicity, infusion-related reactions, and electrolyte disturbances. Patients with preexisting renal issues or imbalances in potassium or magnesium require close monitoring.

Q: What benefits does the liposomal formulation provide over conventional amphotericin B?

A: The liposomal formulation allows for targeted drug delivery and reduces the risk of kidney toxicity, enabling safe administration of higher doses if needed.

Q: How is the dosage of Liposomal Amphotericin B injection determined?

A: Dosage is individualized based on patient weight and clinical indication, commonly ranging from 3 to 5 mg/kg daily, as directed by the attending physician.

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